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metronidazole + Umeta-mimi

Development stage: Unknown
Lead developer: Peking University Shenzhen Hospital
Modality: Live Biotherapeutic Products → Microbiome Therapeutics, Small Molecules
Administration: Oral, Vaginal

Overview

metronidazole + Umeta-mimi is a combination therapy consisting of vaginal metronidazole suppositories and oral Umeta-mimi (also known as Umeta-Miyue) probiotics. Metronidazole is a nitroimidazole small molecule antibiotic that targets anaerobic bacteria by disrupting DNA synthesis, effectively treating the underlying infection in bacterial vaginosis. Umeta-mimi is a live biotherapeutic product containing the probiotic strains Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14, which are intended to restore and maintain a healthy vaginal microbiome to prevent disease recurrence. This combination is currently being evaluated in a Phase 4 clinical trial sponsored by Peking University Shenzhen Hospital for the treatment and prevention of recurrent bacterial vaginosis.

Brand names: Umeta-mimiUmeta-Miyue
Other names: Metronidazole vaginal suppositories and Probiotics (Umeta-mimi)

Targets

DNA

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