Drug intelligence / Profile preview

minoxidil + finasteride

Development stage
Phase 4
Lead developer
Veradermics
Modality
Small Molecules
Administration
Topical, Oral
01

Overview

Minoxidil + finasteride is a fixed-dose combination of two pharmaceutical agents used primarily for the treatment of androgenetic alopecia (male pattern hair loss). Minoxidil acts as a vasodilator that increases blood flow to hair follicles and stimulates their growth. Finasteride is a 5-alpha-reductase inhibitor that reduces the conversion of testosterone to dihydrotestosterone (DHT), a hormone implicated in hair follicle miniaturization and progressive hair loss. The combination can be administered topically or as separate oral/topical regimens. Clinical studies indicate that using both drugs together provides superior efficacy compared to monotherapy with either agent alone while maintaining similar safety profiles[1][2][3][4][5]. This approach addresses different mechanisms underlying male pattern baldness—minoxidil directly stimulates follicles while finasteride targets hormonal causes—resulting in improved outcomes for patients.

Brand names
Formula 82FFormula82FFormula-82FTugainMorr FCoveritHair 4U FHair4U FHair-4U FMinokem-FMinscalp-FTricosilk FBrintop F
Other names
3% minoxidil with 0.1% finasteride lotion3% Minoxidil + 0.1% Finasteride
02

Targets

SRD5A2 (Steroid 5-alpha-reductase type II)KATP channel (ATP-sensitive potassium channel)

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