Drug intelligence / Profile preview

MMR + YF

Development stage
Unknown
Lead developer
Merck
Modality
Live Attenuated Vaccines → Live Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics
Administration
Subcutaneous, Intramuscular
01

Overview

MMR + YF refers to the co-administration of two vaccines: the Measles, Mumps, and Rubella (MMR) vaccine and the Yellow Fever (YF) vaccine. These are both live attenuated virus vaccines that are sometimes administered together in childhood vaccination schedules, particularly in yellow fever endemic areas. Studies have shown that while co-administration is generally effective in producing seroconversion for all antigens, there may be some impact on immunogenicity for certain components, particularly rubella antibody concentrations and yellow fever titers which can be lower when the vaccines are administered simultaneously compared to when they are given separately.

Other names
Measles, Mumps, Rubella + Yellow Fever vaccines
02

Targets

MV (Measles virus)PRR (Pattern recognition receptors)Rubella virus structural polyproteinYFV E (Yellow fever virus envelope protein)

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