Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Modified Ringer's Lactate
- Development stage
- Unknown
- Lead developer
- University of Cape Town
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
Modified Ringer's Lactate is a physiologically balanced crystalloid intravenous solution manufactured by Fresenius-Kabi. It is primarily used as a volume-matched placebo control in clinical research, notably in the CREW-I trial (NCT02807727) led by the University of Cape Town. This trial investigated the potential of Intralipid 20% to mitigate ischemia-reperfusion injury (IRI) in patients undergoing coronary artery bypass grafting (CABG) on cardiopulmonary bypass. As a crystalloid solution, it is composed of inorganic salts and functions to maintain fluid and electrolyte homeostasis without targeting specific biological pathways. It serves as a standard comparator in surgical and critical care settings to ensure volume matching and blinding in experimental studies.
- Other names
- Modified Ringer's Lactate solution
Beyond the preview
Go deeper on Modified Ringer's Lactate.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Modified Ringer's Lactate.