modified ringer's lactate

Modified Ringer's Lactate is an intravenous crystalloid solution that serves as a variation of the standard Ringer's Lactate (also known as Hartmann's Solution). It is typically composed of sodium chloride, sodium lactate, potassium chloride, and calcium chloride, with modifications involving adjustments to electrolyte concentrations or the addition of components like dextrose to meet specific clinical or experimental requirements. In the context of clinical research, such as trials evaluating cardioprotective agents like Intralipid during cardiac surgery, modified versions are often utilized as control solutions or placebos, sometimes specifically formulated by hospital pharmacies to match the appearance of the active intervention. The solution functions by expanding intravascular volume and providing essential electrolytes, while the lactate component acts as a precursor to bicarbonate, helping to maintain acid-base balance and treat metabolic acidosis.

Other names

Modified Ringer's LactateModified Hartmann's SolutionModified RL