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modified Zexie Decoction (Guangdong Provincial Hospital of Traditional Chinese Medicine)
- Development stage
- Unknown
- Lead developer
- The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
- Administration
- Oral
01
Overview
Modified Zexie Decoction is a Traditional Chinese Medicine (TCM) herbal formula derived from the classic Zexie Tang (Alisma Decoction). It is being investigated by The Second Affiliated Hospital of Guangzhou University of Chinese Medicine for the treatment of postmenopausal metabolic syndrome. The formula typically centers on *Alisma plantago-aquatica* (Zexie) and *Atractylodes macrocephala* (Baizhu), modified with additional herbs to target the complex pathophysiology of metabolic syndrome, including dyslipidemia, hypertension, and insulin resistance. In clinical studies, it is administered as either traditional decoction pieces or as modern formula granules to evaluate efficacy, safety, and consistency between these two delivery formats.
- Other names
- Modified Alisma DecoctionJiajian Zexie Tangmodified Zexie Tang
02
Targets
PPARG (Peroxisome proliferator-activated receptor gamma)PPARA (Peroxisome proliferator-activated receptor alpha)
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