mometasone + mupirocin

This is a compounded combination drug containing mometasone (as mometasone furoate), a potent synthetic corticosteroid, and mupirocin, a topical antibacterial agent. The combination is primarily used in compounded formulations for the treatment of nasal and sinus conditions such as allergic rhinitis, sinusitis, nasal polyps, chronic rhinosinusitis, and rhinoconjunctivitis[1]. - **Mometasone** acts by binding to glucocorticoid receptors with high affinity (22 times higher than dexamethasone), modulating gene expression to reduce inflammation through inhibition of pro-inflammatory cytokines and mediators[4][6]. - **Mupirocin** inhibits bacterial protein synthesis by specifically binding to bacterial isoleucyl-tRNA synthetase; it is bacteriostatic at low concentrations but can be bactericidal with prolonged exposure[2][5]. The combination leverages the anti-inflammatory effects of mometasone with the antibacterial action of mupirocin for local therapy in inflammatory or infectious upper airway conditions.

Other names

mometasone + mupirocinmupirocin 5 mg/mometasone furoate 0.6 mg capsules