mometasone furoate nasal spray + antibiotic

Mometasone furoate nasal spray is a synthetic corticosteroid used intranasally to treat and prevent symptoms of allergic rhinitis (seasonal and perennial) and to treat nasal polyps. It works by reducing inflammation through multiple mechanisms, including inhibition of inflammatory cell migration, suppression of mediator release (such as histamine), stabilization of cell membranes, and reduction in capillary permeability. When used in combination with an oral antibiotic—most commonly amoxicillin/clavulanate—it serves as adjunctive therapy for acute or recurrent rhinosinusitis. Clinical studies have shown that adding mometasone furoate nasal spray to antibiotics improves symptom relief compared to antibiotics alone[3][4][5]. The primary indication for this combination is moderate-to-severe acute or recurrent rhinosinusitis confirmed by clinical or imaging criteria.