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momordica charantia + channa striata
- Development stage
- Unknown
- Lead developer
- Universitas Indonesia
- Modality
- Peptides, Small Molecules
- Administration
- Oral
01
Overview
A herbal-animal combination therapy consisting of bitter melon (*Momordica charantia*) extract and snakehead fish (*Channa striata*) powder, primarily investigated for the management of Type 2 Diabetes Mellitus (T2DM). *Momordica charantia* contains bioactive compounds such as charantin, vicine, and polypeptide-p that mimic insulin and inhibit alpha-glucosidase, thereby reducing postprandial glucose levels and improving insulin sensitivity. *Channa striata* is rich in albumin and essential amino acids that provide antioxidant support and may facilitate the repair of pancreatic beta cells. This combination is typically used as an adjunct to standard oral antidiabetic agents like metformin to enhance glycemic control and mitigate oxidative stress associated with chronic hyperglycemia.
- Brand names
- Mocafish
- Other names
- Momordica charantia and Channa striata combinationBitter melon and snakehead fish combinationMormon-Channa
02
Targets
INSR (Insulin receptor)Sucrase-Isomaltase
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