Drug intelligence / Profile preview

moroctocog alfa + isopropyl alcohol

Development stage
Unknown
Lead developer
Pfizer
Modality
Recombinant Proteins and Enzymes
Administration
Intravenous, Topical
01

Overview

Moroctocog alfa + isopropyl alcohol refers to a packaged drug-product listing in which the therapeutic active drug is **moroctocog alfa**, a recombinant B-domain deleted human coagulation factor VIII used for replacement therapy in hemophilia A, while **isopropyl alcohol** reflects a kit-associated antiseptic component such as alcohol swabs rather than a co-active systemic ingredient. Moroctocog alfa functions by replacing deficient factor VIII and restoring the intrinsic coagulation cascade through participation in the factor IXa-mediated activation of factor X, thereby promoting thrombin generation and clot formation in patients with congenital factor VIII deficiency. Commercially this corresponds to moroctocog alfa products such as Xyntha and ReFacto AF that are supplied as intravenous lyophilized recombinant factor VIII kits for on-demand bleeding control, perioperative management, and routine prophylaxis in hemophilia A.

Brand names
Xyntha
Other names
moroctocog alfa + isopropyl alcohol
02

Targets

PS (Phosphatidylserine)F10 (Factor Xa)Coagulation Factor IXa

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