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morphine + propofol
- Development stage
- Unknown
- Lead developer
- AstraZeneca
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
Morphine + propofol is a combination of two drugs used in anesthesia and sedation. Propofol is an intravenous anesthetic agent used for induction and maintenance of general anesthesia, while morphine is an opioid analgesic. When used together, morphine can reduce the necessary propofol maintenance infusion rates and therapeutic blood concentrations. This combination provides both sedative and analgesic effects, making it useful for procedures requiring anesthesia and pain control.
- Other names
- propofol combined with morphine
02
Targets
DOR (Opioid Receptor Delta 1)MOR (Mu opioid receptor)GABRR (GABA-A receptor subunit rho)KOR (Kappa opioid receptor)
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