Drug intelligence / Profile preview

mosapride + aspergillus oryzae pancreatin

Development stage
Unknown
Modality
Therapeutic Enzymes → Recombinant Proteins and Enzymes, Small Molecules
Administration
Oral
01

Overview

This is a combination drug used for the treatment of functional dyspepsia and other digestive disorders. Mosapride is a selective 5-HT4 receptor agonist that promotes acetylcholine release, stimulating gastrointestinal motility and improving symptoms such as bloating, nausea, vomiting, early satiety, and abdominal discomfort[2][3][4]. Aspergillus oryzae pancreatin (米曲菌胰酶片) contains digestive enzymes including amylase, protease, lipase from Aspergillus oryzae and pancreatic enzymes; it aids in the digestion of carbohydrates, proteins, and fats in the stomach and intestines[1][7]. The combination is used to address both impaired gastrointestinal motility (via mosapride) and insufficient digestive enzyme activity (via Aspergillus oryzae pancreatin), providing comprehensive relief for patients with functional dyspepsia.

Other names
枸橼酸莫沙必利 + 米曲菌胰酶片mosapride citrate + oryz-Aspergillus enzyme and pancreatin tablets
02

Targets

HTR4 (5-Hydroxytryptamine receptor 4)

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