moxifloxacin + sorbic acid

Moxifloxacin + sorbic acid (compound 2m) is an experimental small molecule conjugate synthesized by linking the fluoroquinolone antibiotic moxifloxacin with sorbic acid through amide chemistry. This research compound exhibits dual antibacterial and anticancer properties in preclinical studies. Its antibacterial mechanism is derived from moxifloxacin's inhibition of bacterial DNA gyrase and topoisomerase IV, showing high activity against standard bacterial isolates and enhanced potency against multidrug-resistant tuberculosis strains. Additionally, the conjugate has demonstrated significant cytotoxic potential against prostate cancer cells, with IC50 values below 5 µM.

Other names

moxifloxacin-sorbic acid conjugatemoxifloxacin sorbic acid amide