Drug intelligence / Profile preview

Mucinex Night & Day

Development stage
Unknown
Lead developer
Reckitt
Modality
Small Molecules
Administration
Oral
01

Overview

Mucinex Night & Day (also marketed as Mucinex Day & Night) is a line of over-the-counter (OTC) multi-symptom cold, flu, and sinus combination products developed by Adams Laboratories (later acquired by Reckitt Benckiser). These products are typically sold as combo packs containing separate daytime and nighttime formulations. The daytime formulations generally contain active ingredients such as acetaminophen (pain reliever/fever reducer), guaifenesin (expectorant), phenylephrine hydrochloride (nasal decongestant), and dextromethorphan hydrobromide (cough suppressant) to relieve symptoms without causing drowsiness. The nighttime formulations typically include an antihistamine such as doxylamine succinate, diphenhydramine hydrochloride, or triprolidine hydrochloride to relieve runny nose and sneezing while promoting sleep, alongside acetaminophen, phenylephrine, and dextromethorphan. These products are administered orally as caplets, liquid gels, or liquids to temporarily relieve cold, flu, and sinus symptoms.

Brand names
Mucinex Day & NightMucinex Night & Day
Other names
Mucinex Day & Night
02

Targets

PGHS-1 (Prostaglandin G/H Synthase 1)HRH1 (Histamine H1 Receptor)ADRA1A (α1A)SIGMAR1 (Sigma non-opioid intracellular receptor 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)NMDAR (Glutamate receptor ionotropic, NMDA)

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