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mulberry leaf extract + black tea extract
- Development stage
- Preclinical
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Mulberry leaf extract + black tea extract is a combination of botanical extracts commonly formulated as a dietary supplement. Mulberry leaf (Morus spp.) contains compounds that may inhibit carbohydrate absorption and lower blood sugar, while black tea (Camellia sinensis) is rich in polyphenols with antioxidant properties. The rationale for combining these extracts includes potential effects on reducing carbohydrate and fat absorption, modulating lipid profiles, and supporting metabolic health. Preclinical studies suggest the combination can increase fecal fat excretion and improve serum triglyceride/HDL cholesterol ratios but does not significantly reduce weight gain in animal models; high doses may be hepatotoxic[1][3]. This combination is primarily marketed for weight management or metabolic support but lacks robust clinical evidence for efficacy.
- Other names
- mulberry leaf and black tea extractMLE+BTE
02
Targets
Sucrase-IsomaltasePNLIP (Pancreatic triacylglycerol lipase)
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