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multi-allergen oral immunotherapy (Stanford University)

Development stage
Unknown
Lead developer
Stanford University
Modality
Recombinant Proteins and Enzymes
Administration
Oral
01

Overview

A personalized oral immunotherapy (OIT) regimen developed at Stanford University for the treatment of multiple food allergies. The intervention involves the gradual administration of escalating doses of specific food proteins (such as peanut, egg, milk, tree nut, and seed proteins) to which a patient is clinically reactive. The goal is to induce desensitization by modulating the immune system, specifically targeting dendritic cells and reducing IgE-mediated allergic responses. This approach allows for the simultaneous treatment of multiple food allergies using natural food proteins as the active biologic agents. The treatment is tailored to each patient's specific allergy profile based on skin tests or specific IgE levels.

Other names
food proteinscustomized oral immunotherapymulti-allergen OIT
02

Targets

IgE (Immunoglobulin E)

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