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myo-inositol + folic acid + melatonin
- Development stage
- Unknown
- Lead developer
- Lo.Li. Pharma
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Myo-inositol + folic acid + melatonin is a nutritional supplement combination primarily used to manage polycystic ovary syndrome (PCOS) and improve oocyte quality in women undergoing assisted reproductive technologies like in vitro fertilization (IVF). Myo-inositol acts as an insulin sensitizer and a second messenger for follicle-stimulating hormone (FSH), helping to restore ovulatory function and improve metabolic parameters. Folic acid is a critical B-vitamin (B9) essential for DNA synthesis and the prevention of neural tube defects. Melatonin, a hormone typically associated with circadian rhythms, acts as a potent antioxidant within the follicular fluid, protecting oocytes from oxidative stress and enhancing embryo quality. Clinical studies have demonstrated that the synergistic effect of these three components can lead to improved pregnancy outcomes, higher numbers of mature oocytes, and better embryo quality in women with reproductive challenges.
- Brand names
- Inofolic Plus
- Other names
- myo-inositol/folic acid/melatonininositol + folic acid + melatonin
02
Targets
FOLR1 (FRα)MTNR1A (MT1)INSR (Insulin receptor)
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