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N,N,N-trimethyl-2-(phosphonooxy)ethanaminium
- Development stage
- Unknown
- Modality
- Small Molecules
01
Overview
N,N,N-trimethyl-2-(phosphonooxy)ethanaminium is a small molecule also known as phosphocholine. It is the choline ester of phosphoric acid and serves as an intermediate in the biosynthesis of phosphatidylcholine, a major component of biological membranes. In pharmaceutical contexts, its calcium and magnesium salts have been used therapeutically in hepatobiliary dysfunction. The compound itself is not approved for clinical use but has been investigated in early-phase clinical trials[1][2][8]. Its primary mechanism involves acting as a precursor or metabolite within choline and phospholipid metabolism.
- Other names
- Phosphocholine cationEthanaminium, N,N,N-trimethyl-2-(phosphonooxy)-Choline, dihydrogen phosphate (ester)(2-(trimethylazaniumyl)ethoxy)phosphonic acidCholine phosphatePhosphocholine2-(Trimethylazaniumyl)ethyl phosphate
02
Targets
CHKA (Choline kinase)ENPP6 (Glycerophosphocholine cholinephosphodiesterase)
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