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N,N-[2,5-O-dibenzyl-glucaryl]-DI-[valinyl-aminomethanyl-pyridine]

Development stage
Unknown
Modality
Small Molecules
01

Overview

N,N-[2,5-O-dibenzyl-glucaryl]-DI-[valinyl-aminomethanyl-pyridine] is an experimental small molecule inhibitor, also known as INHIBITOR MSA367 and MS3. It is a synthetic compound classified as an amino acid derivative and peptide analog. The molecule features a glucaric acid core with dibenzyl protection at the 2 and 5 positions, linked via amide bonds to two valine-derived aminomethanyl-pyridine moieties. Its primary research use has been as a chemical inhibitor in structural biology studies; it has not been approved for clinical use or assigned any therapeutic indication. There are no reported clinical trials or marketed products containing this compound[1][6][8]. Its mechanism of action is not explicitly described in public sources, but it has been used in the context of HIV Gag-Pol polyprotein inhibition studies[3].

Other names
MS3MS-3MS 3
02

Targets

PR (Progesterone receptor)

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