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N'-(6-aminopyridin-3-yl)-N-(2-cyclopentylethyl)-4-methyl-benzene-1,3-dicarboxamide
- Development stage
- Unknown
- Modality
- Small Molecules
01
Overview
This compound is a synthetic small molecule belonging to the benzamide class. It has been studied as an experimental inhibitor of receptor tyrosine kinases, particularly vascular endothelial growth factor receptor 2 (VEGFR2). Structural studies show it binds to the kinase domain of VEGFR2, but its inhibitory activity is weak (IC50 > 25 μM), indicating low potency. There are no known approved indications or clinical trials for this compound. Its primary relevance is as a tool compound in structural biology and kinase research[1][5][6][8].
- Other names
- N3-(6-aminopyridin-3-yl)-N1-(2-cyclopentylethyl)-4-methylbenzene-1,3-dicarboxamideN3-(6-Aminopyridin-3-Yl)-N1-(2-Cyclopentylethyl)-4-Methylisophthalamide
02
Targets
VEGFR2 (Vascular endothelial growth factor receptor 2)
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