Drug intelligence / Profile preview

N-(2,3-difluoro-benzyl)-4-sulfamoyl-benzamide

Development stage
Unknown
Modality
Small Molecules
01

Overview

N-(2,3-difluoro-benzyl)-4-sulfamoyl-benzamide is an experimental small molecule belonging to the class of n-benzylbenzamides and sulfonamides. It acts as a potent inhibitor of carbonic anhydrase II (CA II), an enzyme involved in the reversible hydration of carbon dioxide. Inhibition of CA II can affect physiological processes such as acid-base balance and fluid secretion. The compound has not been approved for any indication and is primarily studied for its biochemical properties and potential pharmaceutical applications[1][5][9]. Its difluorobenzyl group may enhance metabolic stability and biological activity compared to non-fluorinated analogs[5].

Other names
4-(aminosulfonyl)-N-((2,3-difluorophenyl)methyl)benzamideN-(2,3-difluorobenzyl)-4-sulfamoylbenzamideN-[ (2,3-difluorophenyl)methyl ] - 4 - sulfamoyl - benzamide
02

Targets

CA2 (Carbonic Anhydrase 2)

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