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N-(2-Aminoethyl)-1-aziridineethanamine
- Development stage
- Preclinical
- Modality
- Small Molecules
- Administration
- Unknown / Not Established (experimental Compound; No Approved Routes Documented)
01
Overview
**N-(2-Aminoethyl)-1-aziridineethanamine** is a small molecule experimental drug that acts as an angiotensin-converting enzyme 2 (ACE2) inhibitor. It is chemically an ethane-1,2-diamine derivative where one amino hydrogen is replaced by a 2-(aziridin-1-yl)ethyl group. This compound has been investigated for potential therapeutic use in treating cardiovascular diseases and as an anticoronaviral agent targeting SARS coronavirus infections by inhibiting ACE2. It belongs to the aziridines chemical class and functions primarily through ACE inhibition mechanisms.
- Other names
- N-(2-aminoethyl)-1-aziridine-ethanamineAziridine, 1-(2-((2-aminoethyl)amino)ethyl)-1,2-Ethanediamine, N-(2-(1-aziridinyl)ethyl)-Aziridine, 1-[2-[ (2-aminoethyl)amino]ethyl]-N-[2-(aziridin-1-yl)ethyl]ethane-1,2-diamine
02
Targets
ACE2 (Angiotensin-converting enzyme 2)
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