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N-(6-{[3-(4-Bromophenyl)-1,2-Benzisothiazol-6-Yl]Oxy}Hexyl)-N-Methylprop-2-En-1-Amine
- Development stage
- Unknown
- Modality
- Small Molecules
01
Overview
This compound is a synthetic small molecule belonging to the benzothiazole class. It has been studied as an inhibitor of squalene-hopene cyclase (SHC), an isomerase enzyme involved in sterol and triterpene biosynthesis. The compound binds to the active site of SHC and inhibits its activity with reported IC50 values in the nanomolar range. It has primarily been used as a biochemical tool for structural studies of SHC and related enzymes but does not have any approved therapeutic indications or clinical development status as a pharmaceutical agent[5][6].
- Other names
- (6-{[3-(4-bromophenyl)-1,2-benzothiazol-6-yl]oxy}hexyl)(methyl)(prop-2-en-1-yl)amineallyl(6-(3-(4-bromophenyl)benzo(d)isothiazol-6-yloxy)hexyl)methylamineN-Allyl-6-{[3-(4-bromophenyl)-1,2-benzothiazol-6-yl]oxy}-N-methyl-1-hexanamine
02
Targets
SHC1 (Squalene-hopene cyclase)
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