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N-[(3Z)-5-tert-butyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-ylidene]-N'-(4-chlorophenyl)urea
- Development stage
- Unknown
- Modality
- Small Molecules
- Administration
- Not Applicable (experimental/research Use Only)
01
Overview
A synthetic small molecule with the chemical formula C20H21ClN4O and a molecular weight of approximately 368.9 g/mol. This compound is an experimental agent and has not been approved for any therapeutic use. It is known to act as an inhibitor of mitogen‑activated protein kinase 14 (MAPK14), also known as p38α MAP kinase. The compound has demonstrated inhibitory activity in biochemical assays (IC50 ≈ 196 nM for MAPK14). There are no reported clinical trials or approved indications for this molecule; it remains a research tool in the study of kinase inhibition pathways[6].
- Other names
- N-((3Z)-5-tert-butyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-ylidene)-N'-(4-chlorophenyl)ureaUrea, N-(4-chlorophenyl)-N'-[3-(1,1-dimethylethyl)-1-phenyl-1H-pyrazol-5-yl]-443912–63–8
02
Targets
MAPK14 (p38 mitogen-activated protein kinase alpha)
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