N-[(6-butoxynaphthalen-2-yl)sulfonyl]-L-glutamic acid

N‑[(6‑butoxynaphthalen‑2‑yl)sulfonyl]‑L‑glutamic acid is an experimental small molecule inhibitor of the bacterial enzyme MurD. By inhibiting MurD, which is involved in peptidoglycan biosynthesis, this compound disrupts bacterial cell wall synthesis and leads to bacterial cell death. It has not been approved for clinical use and remains at the experimental stage[1][3]. Its primary mechanism of action is antibacterial via inhibition of a key enzyme in cell wall formation.

Other names

N-(6-butoxynaphthalene-2-sulfonamido)-L-glutamic acid(2S)-2-(6-butoxynaphthalene-2-sulfonamido)pentanedioic acidAcide N-[(6-butoxy-2-naphtyl)sulfonyl]-L-glutamiqueL-glutamic acid, N-[6-butoxy-naphthalenyl)sulfonyl]-