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N-[2-[2-[(4-chlorophenyl)methoxy]ethylamino]ethyl]isoquinoline-5-sulfonamide

Development stage
Preclinical
Lead developer
Eli Lilly
Modality
Small Molecules
01

Overview

N-[2-[2-[(4-chlorophenyl)methoxy]ethylamino]ethyl]isoquinoline-5-sulfonamide is a synthetic small molecule belonging to the class of isoquinoline-5-sulfonic acid amides. This compound is identified as a potential inhibitor of Akt (Protein Kinase B), a crucial enzyme involved in cell survival, proliferation, and metabolism. By inhibiting Akt, the compound is hypothesized to exert antineoplastic and antiviral effects, making it a candidate for the treatment of various cancers and viral infections. Its mechanism of action suggests interference with pathways critical for disease progression.

Other names
ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4-CHLOROBENZYLOXY)ETHYLAMINO)ETHYL)AMIDECHEMBL227381CHEMBL-227381CHEMBL 227381
02

Targets

AKT2 (Rac-beta serine/threonine-protein kinase)

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