N-[4-(2,4-dimethyl-thiazol-5-yl)-pyrimidin-2-yl]-N',N'-dimethyl-benzene-1,4-diamine

This compound is a synthetic small molecule with the chemical formula C17H19N5S and a molecular weight of approximately 325.43 g/mol[3][5]. It belongs to the class of organic compounds known as 2,4,5-trisubstituted thiazoles[3]. The molecule has been studied as an experimental agent and is not approved for clinical use in any country[3]. Its primary mechanism of action is inhibition of cyclin-dependent kinase 2 (CDK2), an enzyme involved in cell cycle regulation. In biochemical assays it demonstrates inhibitory activity against CDK2 with IC50 values in the low nanomolar range (IC50 ≈ 220 nM; Ki ≈ 251 nM)[3][4]. There are no reported clinical indications or marketed formulations for this compound.

Other names

N-[4-(2,4-dimethyl-thiazol-5-yl)-pyrimidin-2-yl]-N',N'-dimethyl-benzene-1,4-diamineN-(4-(2,4-dimethyl-thiazol-5-YL)-pyrimidin-2-YL)-N',N'-dimethyl-benzene-1,4-diamineN4-(4-(dimethyl-1,3-thiazol-5-yl)pyrimidin–2–yl)–N1,N1–dimethylbenzene–1,4–diamine