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Drug intelligence / Profile preview
N-[5-(ethylsulfonyl)-2-methoxyphenyl]-5-[3-(2-pyridinyl)phenyl]-1,3-oxazol-2-amine
- Development stage
- Unknown
- Modality
- Small Molecules
01
Overview
N-[5-(ethylsulfonyl)-2-methoxyphenyl]-5-[3-(2-pyridinyl)phenyl]-1,3-oxazol-2-amine is a synthetic small molecule classified as a phenylpyridine derivative. It is listed in chemical and pharmaceutical databases as an experimental compound. The compound has demonstrated inhibitory activity against vascular endothelial growth factor receptor 2 (VEGFR 2), with an IC50 of 17 nM reported in binding assays. Its primary mechanism of action is presumed to be the inhibition of VEGFR 2 kinase activity, which may have implications for antiangiogenic or antineoplastic research applications[1][2]. There are no approved therapeutic indications or marketed products containing this molecule.
- Other names
- N-[5-(ETHYLSULFONYL)-2-METHOXYPHENYL]-5-[3-(2-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-AMINEN-[5-(ethanesulfonyl)-2-methoxyphenyl]-5-[3-(pyridin-2-yl)phenyl]-1,3-oxazol-2-aminen-[5-(ethylsulfonyl)-2-methoxyphenyl]-5-(3-pyridin-2-ylphenyl)-1,3-oxazol-2-amine
02
Targets
CDK2 (Cyclin-dependent kinase 2)CDK4 (Cyclin-dependent kinase 4)VEGFR2 (Vascular endothelial growth factor receptor 2)
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