Drug intelligence / Profile preview

N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCINE

Development stage
Unknown
Modality
Small Molecules
01

Overview

N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCINE is a synthetic chemical compound characterized by an L-isoleucine residue linked to an epoxide-containing moiety, specifically a (2S,3S)-3-(ethoxycarbonyl)oxiran-2-yl carbonyl group. The oxirane (epoxide) ring is a common electrophilic warhead found in irreversible enzyme inhibitors, particularly those targeting proteases, such as cysteine proteases. This structural feature suggests that the compound likely functions by forming a covalent adduct with a nucleophilic residue in the enzyme's active site, leading to irreversible inhibition. While specific clinical development or primary indications for this exact compound are not widely reported, its chemical structure is consistent with that of a research compound designed to modulate enzymatic activity, potentially as a protease inhibitor.

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