Drug intelligence / Profile preview

N-{2-[(4'-cyano-1,1'-biphenyl-4-yl)oxy]ethyl}-N'-hydroxy-N-methylurea

Development stage
Unknown
Modality
Small Molecules
01

Overview

N-{2-[(4'-cyano-1,1'-biphenyl-4-yloxy]ethyl}-N'-hydroxy-N-methylurea is a synthetic small molecule with the molecular formula C17H17N3O3 and a molecular weight of approximately 311.33 g/mol[1][2][5]. It is classified as an experimental compound and has not been approved for clinical use in any jurisdiction[3][4]. The compound is structurally related to biphenyl derivatives and contains both cyano and hydroxyurea functional groups. It has been studied primarily as a research tool rather than as a therapeutic agent. Structural data indicate it can act as an inhibitor of matrix metalloproteinase enzymes (notably MMP8), based on its co-crystallization with MMP8 in protein databanks[7]. No information about its mechanism of action in humans or animals, clinical indications, or therapeutic applications is available.

Other names
1-[2-(4-(4-cyanophenyl)phenoxy)ethyl]-3-hydroxy-1-methylurea1-{2-[4-(4-cyanophenyl)phenoxy]ethyl}-3-hydroxy-1-methylurea
02

Targets

MMP8 (Neutrophil collagenase)

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