N-acetyl cysteine + rosuvastatin

N-acetyl cysteine + rosuvastatin is a combination therapy consisting of two agents with distinct mechanisms of action. N-acetyl cysteine (NAC) is an antioxidant and precursor to glutathione, used primarily for its mucolytic and hepatoprotective properties, as well as for reducing oxidative stress. Rosuvastatin is a statin that inhibits HMG-CoA reductase, the rate-limiting enzyme in cholesterol biosynthesis, leading to reduced LDL cholesterol and cardiovascular risk. The combination has been studied primarily for the prevention of contrast-induced nephropathy (CIN) in patients undergoing percutaneous coronary intervention (PCI), where it may reduce oxidative stress and improve renal outcomes more effectively than statin monotherapy[1][2][7]. Both agents also have anti-inflammatory effects.

Other names

NAC + rosuvastatinN-acetyl-L-cysteine + rosuvastatin