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N-acetyl cysteine + S-adenosyl methionine + acetyl-L-carnitine + alpha-tocopherol + folate + vitamin B6

Development stage
Preclinical
Lead developer
Galectin Therapeutics
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Administration
Oral
01

Overview

This is a combination dietary supplement containing six active ingredients: - **N-acetyl cysteine (NAC):** An antioxidant and precursor to glutathione, used for its detoxification, mucolytic, and neuroprotective properties. It is also known for lowering homocysteine levels and supporting brain health[3][4][5][6]. - **S-adenosyl methionine (SAMe):** A methyl donor involved in numerous biochemical processes including neurotransmitter synthesis. It has been studied for depression, osteoarthritis, liver disorders, and as a homocysteine-lowering agent[2][6]. - **Acetyl-L-carnitine:** An amino acid derivative that supports mitochondrial energy metabolism and may have neuroprotective effects. - **Alpha-tocopherol:** The most biologically active form of vitamin E; an antioxidant that protects cell membranes from oxidative damage. - **Folate:** A B-vitamin essential for DNA synthesis and repair; it also helps lower homocysteine levels when combined with other B vitamins[6]. - **Vitamin B6:** Another key cofactor in amino acid metabolism and homocysteine reduction. The combination targets oxidative stress reduction, support of methylation pathways (including lowering of homocysteine), mitochondrial function enhancement, membrane protection from free radicals, and overall neurological health. Such combinations are often marketed as cognitive or metabolic support supplements but are not approved pharmaceuticals.

02

Targets

GSH (Glutathione synthesis / redox)Neuraminidase

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