Drug intelligence / Profile preview

NADH + coenzyme q10

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

NADH + coenzyme q10 is a combination dietary supplement containing two naturally occurring compounds involved in cellular energy production. - **NADH** (nicotinamide adenine dinucleotide + hydrogen) is a coenzyme found in all living cells that plays a key role in the mitochondrial electron transport chain, facilitating ATP (energy) production. Supplementation with NADH has been studied for its potential to reduce fatigue and support cognitive function, particularly in conditions like chronic fatigue syndrome. - **Coenzyme Q10** (CoQ10 or ubiquinone) is a fat-soluble antioxidant present in every cell membrane and essential for mitochondrial energy metabolism. It helps transfer electrons within the oxidative respiratory chain to produce ATP and also acts as an antioxidant protecting cells from oxidative stress. CoQ10 supplementation has been investigated for heart failure, migraine prevention, neurodegenerative diseases such as Parkinson’s disease, mitochondrial disorders, and general support of cellular health[1][2][3][4][5]. The combination of these two supplements aims to synergistically enhance ATP production and provide antioxidant protection. Clinical studies suggest that combined supplementation may help reduce fatigue—especially in chronic fatigue syndrome—and improve mental focus[3][5].

Other names
NADH and CoQ10NADH plus coenzyme Q10NADH + CoQ10
02

Targets

NADH:ubiquinone oxidoreductase subunit familybc1 complex (Cytochrome bc1 complex (plasmodium))

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