Drug intelligence / Profile preview

nano hydroxyapatite reinforced glass ionomer (GCP Dental)

Development stage
Unknown
Lead developer
Cairo University
Modality
Device-based Delivery → Drug Delivery Systems, Nanoparticles → Drug Delivery Systems
Administration
Topical
01

Overview

Nano hydroxyapatite reinforced glass ionomer is an experimental dental restorative material developed by incorporating nano-sized hydroxyapatite (nHAp) particles into a conventional glass ionomer cement (GIC) matrix. Hydroxyapatite is a biocompatible material chemically and structurally similar to human tooth enamel and dentin. The addition of these nanoparticles is intended to enhance the mechanical properties of the cement, such as compressive and tensile strength, while improving its bioactivity. Mechanistically, the material promotes the remineralization of the tooth structure by releasing calcium and phosphate ions, which helps to integrate the restoration with the natural dentin and enamel. It is primarily being evaluated for the treatment of root caries, particularly in geriatric patients, where its superior marginal seal and ion-releasing properties offer advantages over traditional restorative materials.

Other names
nHAp-GICnano-hydroxyapatite modified glass ionomer cementnano hydroxyapatite reinforced glass ionomer cement

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