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naphazoline + pheniramine (Denver Farma)
- Development stage
- Unknown
- Lead developer
- Denver Farma
- Modality
- Small Molecules
- Administration
- Ophthalmic
01
Overview
ALIVIALUX is an ophthalmic combination drug developed and marketed by Denver Farma. It is indicated for the temporary relief of symptoms associated with allergic conjunctivitis, such as ocular redness, itching, and congestion. The formulation consists of naphazoline hydrochloride, a sympathomimetic agent that acts as an alpha-adrenergic agonist to induce vasoconstriction of the conjunctival blood vessels, and pheniramine maleate, a first-generation antihistamine that competitively inhibits H1 receptors to reduce allergic inflammation and pruritus. The product is typically administered topically as eye drops.
- Brand names
- ALIVIALUX
- Other names
- naphazoline hydrochloride + pheniramine maleate
02
Targets
HRH1 (Histamine H1 Receptor)ADRA1A (α1A)
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