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naproxen + cholecalciferol
- Development stage
- Unknown
- Lead developer
- Humax
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
OKSON D3 is a fixed-dose combination pharmaceutical product developed and marketed by Humax Pharmaceutical, a Colombian subsidiary of Bausch Health. It contains the nonsteroidal anti-inflammatory drug (NSAID) **naproxen** and **cholecalciferol** (Vitamin D3). The product is indicated for the symptomatic treatment of chronic inflammatory conditions, including rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis, particularly in patients who are at risk of Vitamin D deficiency. Naproxen provides relief from pain and inflammation by inhibiting the cyclooxygenase enzymes (COX-1 and COX-2), while cholecalciferol helps maintain bone health and calcium balance, which is often compromised in patients with chronic joint diseases or those on long-term medication.
- Brand names
- OKSON D3
- Other names
- Naproxen/Vitamin D3Naproxen/Cholecalciferol
02
Targets
PGHS-1 (Prostaglandin G/H Synthase 1)VDR (Vitamin D receptor)
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