Drug intelligence / Profile preview

National Inst. of Pharma Education and Research (NIPER) MMP9 compound 10 g

Development stage
Preclinical
Lead developer
National Institute of Pharmaceutical Education and Research
01

Overview

National Inst. of Pharma Education and Research (NIPER) MMP9 compound 10 g: sourced facts only. name: "Target-based study for compound 10 g revealed excellent inhibition of MMP9, as evidenced by Western blotting, Immunofluorescence study and MMP9 enzyme inhibition assay." [PMID:40716158]; target: "Target-based study for compound 10 g revealed excellent inhibition of MMP9, as evidenced by Western blotting, Immunofluorescence study and MMP9 enzyme inhibition assay." [PMID:40716158]; developer: "Department of Chemical Sciences, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad 500037, India." [PMID:40716158]; stage: "Among them, compound 10 g was found to be 16-fold selective towards the HCT-116 cancer cell line with an IC50 value of 1.54 ± 0.06 μM compared to a non-cancerous cell line, i.e., HEK293." [PMID:40716158]

02

Targets

MMP9 (Matrix metalloproteinase-9)

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