Drug intelligence / Profile preview

National Inst. of Pharma Education and Research-Ahmedabad (NIPER-A) PKM2 compound 7d

Development stage
Preclinical
Lead developer
National Institute of Pharmaceutical Education and Research, Ahmedabad
01

Overview

National Inst. of Pharma Education and Research-Ahmedabad (NIPER-A) PKM2 compound 7d: sourced facts only. name: "Herein, we report the rational development of an imidazopyridine-based thiazole derivative 7d as an anticancer agent inhibiting PKM2." [PMID:38408027]; target: "Herein, we report the rational development of an imidazopyridine-based thiazole derivative 7d as an anticancer agent inhibiting PKM2." [PMID:38408027]; developer: "Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A), Opposite Airforce station, Palaj, Gandhinagar, Gujarat 382355, India." [PMID:38408027]; stage: "In vivo, 7d outperformed lapatinib in tumor regression." [PMID:38408027]

02

Targets

PKM2 (Pyruvate kinase M2 isoform)

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