Ndelta-(N'-Sulphodiaminophosphinyl)-L-Ornithine

Ndelta-(N'-Sulphodiaminophosphinyl)-L-Ornithine is a synthetic small molecule derivative of L-ornithine, characterized by the addition of a sulphodiaminophosphinyl group at the delta position. It has been studied primarily as an experimental compound and is not approved for clinical use. The compound has been used in structural biology studies as an inhibitor or ligand to probe ornithine transcarbamylase (OTC), an enzyme involved in the urea cycle that catalyzes the transfer of a carbamoyl group from carbamoyl phosphate to ornithine, forming citrulline. This molecule acts as a transition-state analog or competitive inhibitor for OTC, providing insights into enzyme mechanism and structure[1][4][6]. There are no known therapeutic indications or marketed formulations.

Other names

NDELTA-(N'-SULPHODIAMINOPHOSPHINYL)-L-ORNITHINEPSQN~5~-[(R)-Amino(sulfoamino)phosphoryl]-L-ornithine