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niacinamide + arbutin + scutellaria baicalensis root extract + centella asiatica extract + camellia sinensis leaf extract
- Development stage
- Unknown
- Modality
- Recombinant Proteins and Enzymes, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Topical
01
Overview
A multi-ingredient topical skincare formulation composed of niacinamide, arbutin (commonly alpha arbutin), Scutellaria baicalensis root extract (Baikal skullcap), Centella asiatica extract, and Camellia sinensis leaf extract (green tea). This combination targets hyperpigmentation, uneven skin tone, redness, irritation, and photoaging. - **Niacinamide** (vitamin B3): Reduces melanosome transfer, fades dark spots and hyperpigmentation, supports skin barrier function, improves moisture retention, refines texture, and regulates oil production[1][2][4][7]. - **Arbutin** (usually alpha arbutin): Inhibits tyrosinase activity, reducing melanin synthesis and the appearance of dark spots and discoloration[1][4][5][7]. - **Scutellaria baicalensis root extract**: Rich in antioxidant flavonoids (such as baicalin), anti-inflammatory, brightens post-acne marks, soothes irritation, and protects against oxidative stress[3][6][9]. - **Centella asiatica extract**: Promotes wound healing, calms inflammation, supports collagen synthesis (noted properties from general scientific and cosmetic literature). - **Camellia sinensis leaf extract**: Antioxidant, anti-inflammatory, protects against environmental stressors, and reduces free radical damage (general scientific consensus). Combined, these ingredients provide comprehensive skin brightening, barrier strengthening, and protective benefits. This product is used in topical cosmetic and cosmeceutical preparations, not as a systemic pharmaceutical.
- Other names
- niacinamide + arbutin + Scutellaria baicalensis root extract + Centella asiatica extract + Camellia sinensis leaf extractniacinamide-Ungku Shahrin Medical Aesthetic Research & Innovation (USMARI) Centre-post-inflammatory hyperpigmentation
02
Targets
TYR (Tyrosinase)Melanosome transfer machinery
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