Drug intelligence / Profile preview

nicotinamide mononucleotide + DC cell vaccine

Development stage
Unknown
Lead developer
Shanghai Cell Therapy Group
Modality
Dendritic Cell Vaccines → Immune Effector Cells → Other Cell Types → Cell Therapies, Small Molecules, Vaccines & Immunotherapeutics
Administration
Oral (nmn), Injection (dc Cell Vaccine)
01

Overview

This is a **combination therapy** consisting of **nicotinamide mononucleotide (NMN)** and a **dendritic cell (DC) vaccine**. NMN is a precursor of NAD^+, a key coenzyme involved in cellular metabolism, DNA repair, and regulation of immune responses. It is investigated for its potential to ameliorate aging-related disorders and to support cellular health, including effects on DNA repair, mitochondrial function, autophagy, and immune cell activity[9]. The DC cell vaccine is an immunotherapy modality where dendritic cells, the body's primary antigen-presenting cells, are activated and injected to stimulate a robust anti-tumor immune response by priming T cells and inducing cytotoxic lymphocyte and memory T cell formation[8][6][4][2]. The combination is being studied for its ability to enhance the immunotherapeutic and antitumor effects of DC-based vaccination post-surgery in oncology settings, aiming to improve patient outcomes, immune system diversity, and biomarkers of biological age[5].

Brand names
Vital NAD
Other names
nicotinamide mononucleotide + dendritic cell vaccine
02

Targets

PDCD1 (Programmed cell death protein 1 receptor)CTLA-4 (Cytotoxic t-lymphocyte–associated protein 4)

Beyond the preview

Go deeper on nicotinamide mononucleotide + DC cell vaccine.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on nicotinamide mononucleotide + DC cell vaccine.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call