Drug intelligence / Profile preview

NK510 + atezolizumab

Development stage
Unknown
Lead developer
Genentech
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

NK510 + atezolizumab is a **combination therapy** under investigation for the treatment of advanced gastric cancer. NK510 is an investigational drug (modality not fully specified in public records) and atezolizumab is a fully humanized monoclonal antibody that targets programmed death-ligand 1 (PD-L1), functioning as an immune checkpoint inhibitor. The combination is being tested for its safety and efficacy, where NK510 is administered alongside atezolizumab, a PD-L1 inhibitor, with the goal of amplifying anti-tumor immune responses. Trials specifically mention use in relapsed and refractory advanced gastric cancers, with atezolizumab provided according to standard dosing instructions. The regimen design allows evaluation of NK510 both as monotherapy and combined with atezolizumab in separate trial arms[1].

Other names
NK510 + atezolizumab
02

Targets

CD274 (Programmed cell death protein 1 ligand 1)

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