Drug intelligence / Profile preview

Noglux (Bioksan, eda923)

Development stage
Unknown
Lead developer
Bioksan
Modality
Live Biotherapeutic Products → Microbiome Therapeutics, Small Molecules
Administration
Oral
01

Overview

Noglux is a multi-ingredient dietary supplement developed by Bioksan for the management of prediabetes and the prevention of type 2 diabetes. The formulation combines standardized white mulberry (*Morus alba*) leaf extract (Reducose®), fenugreek (*Trigonella foenum-graecum*) seed extract, inulin, *Lactiplantibacillus plantarum* A7 probiotic, niacin, zinc, and chromium. The primary active component of white mulberry leaf extract, 1-deoxynojirimycin (DNJ), acts as a competitive alpha-glucosidase inhibitor to delay carbohydrate absorption and reduce postprandial glycemic spikes. Fenugreek extract acts as an AMPK activator to improve insulin sensitivity. In clinical studies, Noglux has demonstrated significant efficacy in improving glycemic control, lipid profiles, and blood pressure, while reducing overall cardiovascular risk (SCORE2) in patients with prediabetes.

Brand names
Noglux
Other names
white mulberry leaf-based nutraceutical
02

Targets

AMPK (Adenosine monophosphate–activated protein kinase)Sucrase-Isomaltase

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