norethisterone enantate + estradiol valerate

Norethisterone enantate + estradiol valerate is a combined injectable contraceptive containing two hormones: norethisterone enantate, a synthetic progestogen (progestin), and estradiol valerate, a synthetic estrogen. Administered as an intramuscular depot injection once monthly, it provides effective contraception by suppressing ovulation and altering the endometrium and cervical mucus to prevent pregnancy. The combination is also used in hormone replacement therapy for menopausal symptoms and prevention of osteoporosis in postmenopausal women. After injection, both esters are hydrolyzed to their active forms—norethisterone and estradiol—which act as agonists at the progesterone receptor and estrogen receptor, respectively[1][4][5][7].

Brand names

MesigynaChinese Injectable No. 3EfectimesGinediolMesilarMeslartMesoceptMesygestNofertylNofertyl LafrancolNoregynaNorestrinNorifamNorigynonNostidynSexsegSolouna

Other names

norethisterone enanthate + estradiol valerate injection