normal saline placebo (Medical University of South Carolina)

Normal saline (0.9% sodium chloride solution) is used as a placebo control in a randomized, double-blind clinical trial conducted by the Medical University of South Carolina. The trial, titled "Low Dose Vasopressin for Renal Protection During Liver Transplantation," evaluates whether a low-dose vasopressin infusion can preserve kidney function in patients undergoing liver transplant surgery. In this study, the normal saline placebo is administered via an internal jugular catheter at a rate of 6.25 mL/hr, matching the infusion rate of the active vasopressin arm to maintain blinding. It serves as an inert comparator to assess the efficacy of vasopressin in preventing post-operative renal failure.

Other names

0.9% sodium chloride0.9% NaClnormal saline