normal saline placebo (University of California, Davis)

This is a placebo control used in a Phase 4 randomized, double-blind clinical trial (NCT04166877) conducted by the University of California, Davis. The placebo consists of normal saline (0.9% sodium chloride solution) administered intravenously to critically ill trauma patients with acute pain. It serves as an inert comparator to evaluate the efficacy of continuous intravenous magnesium sulfate in reducing opioid requirements and pain scores. As a placebo, it contains no active pharmacological ingredients intended for pain management and is designed to match the volume and administration rate of the experimental drug to maintain the study's blinding.

Other names

0.9% sodium chloridenormal salinesalt solution