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NVP-1805-R1 + NVP-1805-R2

Development stage: Unknown
Lead developer: NVP Healthcare
Modality: Small Molecules
Administration: Oral

Overview

NVP-1805-R1 + NVP-1805-R2 is an investigational oral combination of two small molecule drugs developed by Navipharm and evaluated by NVP Healthcare. The combination has been studied in Phase 1 clinical trials to assess pharmacokinetic interactions, safety, and tolerability when coadministered in healthy adult volunteers. Both components—NVP-1805-R1 and NVP-1805-R2—are also being investigated individually. The primary therapeutic area under investigation is cardiovascular diseases, with additional interest in vascular diseases. No detailed mechanism of action or molecular targets have been disclosed publicly for either component[1][3][6].

Brand names: Duowell A
Other names: telmisartan + amlodipine + rosuvastatin

Targets

HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)AGTR1 (Angiotensin II Type-1 receptor)CACNA1C (Voltage-dependent L-type calcium channel subunit alpha-1C)

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