oleoylethanolamide + ginger extract + lavender essential oil

A combination dietary supplement consisting of **oleoylethanolamide** (OEA), **ginger extract**, and **lavender essential oil**, each with evidence for bioactivity in inflammation, oxidative stress, and mood regulation but not commonly marketed under a unified brand or fixed-dose formulation. - **Oleoylethanolamide** is an endogenous lipid mediator that acts primarily as a **peroxisome proliferator-activated receptor alpha (PPAR-α) agonist** and is implicated in the regulation of lipid metabolism, appetite, neuroprotection, and anti-inflammatory responses. Clinical studies in humans have shown supplementation with OEA decreases levels of inflammatory cytokines like IL-6 and TNF-α and reduces oxidative stress markers in obese individuals, likely via activation of PPAR-α, inhibition of NF-κB signaling, and suppression of downstream pro-inflammatory mediators[1]. - **Ginger extract** is derived from the root of **Zingiber officinale** and contains active compounds (e.g., gingerols, shogaols) with **anti-inflammatory**, antiemetic, analgesic, and antioxidant effects, targeting pathways such as COX, LOX, and NF-κB. - **Lavender essential oil** is a volatile oil from **Lavandula angustifolia** with a primary clinical profile as an **anxiolytic, sedative, mild analgesic, and anti-inflammatory** agent. It acts through several mechanisms, including modulation of GABAergic signaling and G protein-coupled receptors, and exerts topical antimicrobial and antioxidant activities[2][3][4][5]. This combination's potential uses may include adjunctive support for **obesity, inflammation, anxiety, and mood regulation**. Scientific research exists on the single components but not on the efficacy, safety, or regulatory status of this exact three-ingredient combination in a singular formulation.