Drug intelligence / Profile preview

Omegaven + Dipeptiven

Development stage
Unknown
Lead developer
Fresenius Kabi
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Intravenous
01

Overview

Omegaven + Dipeptiven is a combination used in parenteral nutrition, particularly for pediatric patients with parenteral nutrition-associated cholestasis (PNAC) or those requiring specialized intravenous nutritional support. - **Omegaven** is a fish oil-based lipid emulsion rich in omega-3 fatty acids (EPA and DHA), providing essential fatty acids and calories. It is indicated as a source of calories and fatty acids in pediatric patients with PNAC, supporting growth, development, and improvement of liver function parameters[1][3][5][6]. - **Dipeptiven** contains the dipeptide L-alanyl-L-glutamine, which serves as a stable source of glutamine for intravenous administration. Glutamine is considered conditionally essential during critical illness or stress; it supports protein synthesis, immune function, gut integrity, and nitrogen balance. This combination provides both lipid energy (from Omegaven) and amino acid supplementation (from Dipeptiven), often used together in total parenteral nutrition regimens for critically ill or malnourished patients who cannot tolerate enteral feeding[2].

Brand names
DipeptivenOmegaven
Other names
fish oil triglycerides injectable emulsion + L-alanyl-L-glutamine dipeptide solution
02

Targets

CYP4A (Cytochrome P450 4A family)

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