Drug intelligence / Profile preview

Oracure (Amoun Pharmaceutical)

Development stage
Unknown
Lead developer
Amoun Pharmaceutical
Modality
Small Molecules
Administration
Topical
01

Overview

Oracure is a topical oral gel used for the symptomatic relief of painful inflammatory conditions of the mouth, including oral mucositis, mouth ulcers, and gingivitis. It is a combination product typically formulated with an analgesic and anti-inflammatory agent (choline salicylate), a local anesthetic (lidocaine), and an antiseptic (benzalkonium chloride). Choline salicylate provides relief from pain and inflammation by inhibiting cyclooxygenase enzymes, while lidocaine offers rapid local anesthesia by blocking voltage-gated sodium channels. Benzalkonium chloride acts as a broad-spectrum antiseptic to prevent secondary microbial infections in damaged oral mucosa. In clinical research, Oracure has been utilized as a component of conventional symptomatic treatment regimens for managing radiation-induced oral mucositis in patients with head and neck cancer.

Brand names
Oracure
02

Targets

PGHS-1 (Prostaglandin G/H Synthase 1)SCN1A (Voltage-gated sodium channel protein type 1 subunit alpha)

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